L-Arginine: Effect as a combined supplement

Vascorin® Arginin PLUS: To aid vascular disorders

Vascorin® Arginin PLUS by ZeinPharma® contains L-arginine base, folic acid, vitamin B6 and metylcobalmin (vitamin B12). The interaction of these nutrients provides an aid in disorders of the vascular system such as endothelial dysfunction, elevated homocysteine levels or slightly elevated blood pressure. Folic acid, vitamin B6 and vitamin B12 keep homocysteine at a constant level. This improves the uptake of L-arginine in the cells and the synthesis of nitric oxide (NO) from L-arginine. NO causes vasodilatation and relaxation.

✅ L-Arginine Base consists of at least 98% L-Arginine.

✅ The pH-value amounts to 10,5 to 12 according to international standards and is considered to be very well digestible.

What is L-Arginine?

L-Arginin aufspaltung von Formelsatz

L-Arginine, also commonly known as arginine, is a semi-essential proteinogenic amino acid. “Semi-essential” means that you can not only ingest this amino acid through your diet, but also produce it out of various vitamins and amino acids. “Proteinogen” means that your body can produce not only enzymes and neurotransmitters from L-arginine, but also endogenous tissue such as skin, hair and muscles. However, L-arginine is also said to have a special property that distinguishes it from other amino acids.

Effect of L-Arginine – Simply Explained

With four nitrogen groups, L-arginine contains more nitrogen than other amino acids. For this reason, your body is able to produce the vasodilator nitric oxide (NO) from L-arginine alone. This molecule regulates vasodilatation and is therefore also involved in the control of blood pressure and blood circulation. This makes it useful in cases of vascular disorders such as endothelial dysfunction or slightly elevated blood pressure.

What is the recommended dosage of L-Arginine?

The demand for L-arginine can vary greatly from person to person because it depends on various factors:

  • Age
  • general health
  • possible illnesses
  • physical stress through sport or work
  • stress

For therapeutic purposes, the recommended daily dose of L-arginine is approximately 3,000 mg per day. However, it is difficult to take such an amount in the long term solely through diet. One capsule of Vascorin® Arginin PLUS contains 750 mg L-Arginine. With the recommended daily dosage of four capsules, you will get a daily L-Arginine intake of 3,000 mg, which corresponds exactly to the average recommended daily dosage.

1 mg

Per Vascorin® Arginin PLUS Capsule
(4 capsules/daily dose)

750 mg

Recommended daily dose L-Arginine
(Therapeutic Use)

L-Arginine for endothelial dysfunction

Endothelial dysfunction is a general dysfunction of the endothelium – a thin layer of cells lining the interior of vessels. A disturbed function of the endothelium can affect the regulation of vasodilatation and the permeability of your vessels and is suspected of promoting arteriosclerosis in the long term.

The regular intake of L-arginine can be used to aid endothelial dysfunction. L-arginine has the following effect: During nitrogen synthesis, L-arginine is converted into the so-called EDRF factor. This factor enters the muscle layer of your vessels and activates a soluble enzyme – guanylate cyclase. The activation of this enzyme in turn ensures a lower tension in the smooth muscles and vessels. The result is a natural vasodilatation, which can benefit endothelial dysfunction in the long term.

With Vascorin® Arginin PLUS from ZeinPharma® you get a highly bioavailable L-Arginine preparation that additionally supplies your body with further nutrients that can be used to support endothelial dysfunction, elevated homocysteine levels and slightly elevated blood pressure.

L-Arginine for potency disorders

The blood circulation-promoting properties of L-arginine can also have an effect on the male sex organ and promote an erection.

Since erectile dysfunction can have different causes, you should always consult a doctor for a precise diagnosis. L-Arginine should only be regarded as a supportive treatment option, which cannot replace a medical therapy.

Vascorin® Arginin PLUS: for elevated homocysteine levels

Homocysteine is a naturally occurring, non-proteinogenic amino acid. This means that your body cannot use it to form its own tissue such as skin, hair or muscles. The main task of homocysteine is to support the formation of proteinogenic amino acids. A too high occurrence of the amino acid is also known as hyperhomocysteinemia and can be associated with an increased risk of various cardiovascular diseases.

L-arginin hilft bei hohem Homocysteinspiegel

What causes elevated homocysteine levels?

An increase in homocysteine levels due to a genetic predisposition occurs in only about one third of all people affected. The exact causes for the increased levels are not yet known. A frequent cause, however, is a lack of nutrients as a result of malnutrition. The body can only break down homocysteine with the help of the micronutrients vitamin B12, vitamin B6 and folic acid. If these are not available in sufficient quantities, the homocysteine level rises continuously. In addition, other influences are also suspected of increasing homocysteine levels: 

  • Hypothyroidism
  • kidney diseases
  • increased alcohol consumption
  • medicines like metformin, methotrexate, or cholestyramine

The risk of increased homocysteine levels

In general, even a slightly elevated homocysteine level is considered a risk factor for vascular diseases such as strokes and thromboses. This leads to a demonstrable damage of the vascular endothelium, which can promote arteriosclerosis and all associated diseases. Basically, elevated homocysteine levels can represent a risk for the following diseases:

  • Arteriosclerosis
  • thrombosis
  • myocardial infarction
  • apoplexy

In addition, elevated homocysteine levels are also suspected of promoting the development of various dementia diseases, in particular Alzheimer’s disease. One study even revealed the alarming finding that an increase in serum homocysteine levels of 5 µmol/l could lead to a 40 percent increase in the risk of Alzheimer’s disease.

When is the homocysteine level too high?

Many sufferers do not even know that they suffer from elevated homocysteine levels. This is because homocysteine levels are usually only measured if a patient has been diagnosed with calcifications of the brain, heart, leg or neck vessels since childhood. In addition, the value is also determined in heart attack, stroke or thrombosis patients. Values between 5 and 10 µmol/l are considered normal. We speak of an elevated homocysteine level in everything that goes beyond this.

For the determination of the homocysteine value a small blood sample from the finger is sufficient. If necessary, this can also be done as part of a general blood test. If you have a tendency to nutrient deficiencies, you should have your homocysteine level tested as regularly as possible – preferably once a year. Because the earlier you determine the elevated values, the easier it is for you to counteract them.

Older people in particular often suffer from increased homocysteine levels due to low nutrient intake. A dietary supplement with vitamin B12, B6 and folic acid can be used to support this. This is because they help your body to break down the excess amino acids again. Vascorin® Arginine PLUS by ZeinPharma® contains L-Arginine as well as the mentioned micronutrients, so it can support you in a comprehensive prevention of vascular diseases.

Vascorin® Arginin PLUS contains Vitamin B12, Vitamin B6 and Folic Acid

A sufficient supply of vitamin B12, B6 and folic acid is of great importance both for prevention and treatment of elevated homocysteine levels. By supplementing this with Vascorin® Arginine PLUS, you can help your body break down homocysteine and counteract vascular diseases such as thromboses, heart attacks and strokes.

What is Vitamin B12?

Vitamin B12 is one of the so-called “essential vitamins”. This means that your body cannot produce vitamin B12 itself, which is why you must always supply it through your diet. The vital vitamin is involved in cell division, energy metabolism, fat metabolism and hormone production. A vitamin B12 deficiency can not only contribute to increased homocysteine levels, but also have other health consequences:

  • Nerve damage
  • energy metabolism disturbance
  • Disorders of the hormonal balance
  • digestive problems
  • inflammations

In order to prevent a vitamin B12 deficiency, the German Society for Nutrition for Adults recommends that men and women take 4.0 µg per day. Pregnant and breastfeeding mothers should even consume up to 5.5 µg per day. For children, the recommended daily dose is 0.5 to 4.9 µg per day. Vascorin® Arginine PLUS even contains methylcobalmin. This is vitamin B12 in a bioactive form. It provides your body with 4.0 µg vitamin B12 when taking the daily dosage recommendation.

What does vitamin B6 do?

Vitamin B6 is one of the water-soluble vitamins that are characterized by the fact that they can hardly be stored by the human body. Therefore, a constant supply via the diet is also necessary here. Vitamin B6 is said to be involved in various central metabolic processes, such as protein metabolism or the formation and protection of nerve connections. 

Since vitamin B6 is found in many plant foods, deficiency symptoms are rather rare. The German Nutrition Society recommends a daily intake of 1.6 mg for men and about 1.4 mg for women. For children, on the other hand, a daily dose of 0.1 to 1.2 mg should be sufficient, depending on their age. A regular intake of vitamin B6 not only keeps homocysteine in check, but can also contribute to an unhindered protein metabolism and a healthy immune system. With four capsules of Vascorin® Arginine PLUS you supply your body with 3 mg vitamin B6.

What is folic acid?

Folic acid is an essential vitamin that is also known as folate or vitamin B9. Folic acid is involved in amino acid metabolism and is believed to play a role in all physical growth processes. These include cell division and the multiplication of the genetic material. In most cases, folic acid deficiency is caused by an unbalanced diet or alcohol abuse. However, deficiency symptoms can also occur due to increased demand during pregnancy and breastfeeding.

A lack of folic acid usually leads to a faulty regeneration of the red blood cells, from which a dangerous anaemia can develop. During pregnancy, this can even lead to developmental disorders in the unborn child. According to the German Nutrition Society, the daily folic acid requirement for adults is around 300 µg. However, the daily requirement of pregnant women and nursing mothers can increase to up to 550 µg. Depending on their age, children can manage with 60 to 240 µg per day. By taking four Vascorin® Arginin PLUS capsules daily, you provide your body with 400 µg of folic acid.

The advantages of Vascorin® Arginine PLUS

Vascorin L-Arginine Plus contains L-Arginine Base and is suitable for supportive use in cases of vascular disorders, elevated homocysteine levels and slightly elevated blood pressure. It offers the following advantages:

  • L-Arginine Base offers high bioavailability
  • Support in covering vitamin B12-, B6 and folic acid requirements
  • Scientifically proven efficacy
  • Premium quality "Made in Germany"

Vascorin® Arginin PLUS – Intake Recommendation

One pack of Vascorin® Arginin PLUS contains 120 capsules. With a recommended dosage of four capsules per day, this corresponds to the ration for exactly one month. The capsules should always be taken whole and with at least 200 ml of water.

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